Specimens should be shipped at room temperature in a leak-proof, rigid container with overnight delivery. To discuss minimum acceptable specimens for sample types not listed, please contact Allele Diagnostics.
For maternal sample:
- Peripheral blood: 3-5 mL EDTA
- iSWAB™ - DNA Collection Kit (4 swabs) Order a kit
- DNA2: 2 μg
For fetal sample:
- Prenatal specimen or cord blood: See requirements for additional testing that is ordered
- Rule out presence of maternal cell contamination within a fetal specimen.
The potential presence of maternal cells within a prenatal specimen (amniotic fluid, CVS, POC) causes risk for interpreting DNA based test results inaccurately. In order to have complete confidence that the test results are indicative of the fetal DNA, the maternal blood genotype is compared to the fetal genotype, derived from amniocyte DNA, chorionic villus DNA, or POC DNA. This assay assesses at least 13 chromosomal markers utilizing a PCR-based assay. This study detects and quantifies the presence of maternal DNA within the prenatal sample.